High Performance Liquid Chromatographic Determination of Colchicine-alkaloid from the Tissues and Biological Fluid of Bovine Poisoned by the Corm of Autumn Crocus (Colchicum autumnale L.)
نویسندگان
چکیده
منابع مشابه
A fatal case of autumn crocus (Colchicum autumnale) poisoning in a heifer: confirmation by mass-spectrometric colchicine detection.
A heifer developed severe signs of acute gastrointestinal irritation 48 hr after ingesting fresh leaves of Colchicum autumnale growing on a damp meadow. Confirmation of the suspected toxicosis was obtained by detecting colchicine in serum and urine using liquid chromatography coupled with tandem mass spectrometry using atmospheric pressure chemical ionization. Although the serum colchicine conc...
متن کاملComparison of enterotoxicity between autumn crocus (Colchicum autumnale L.) and colchicine in the guinea pig and mouse : enterotoxicity in the guinea pig differs from that in the mouse.
Autumn crocus poisoning of cattle is characterized by severe diarrhea caused by alkaloid colchicine. Previously, we examined pathologically this poisoning in cattle and reported that enterotoxic lesions were closely associated with apoptosis. To examine enterotoxicity of autumn crocus more precisely, a reproductive study was performed using guinea pigs and mice, and pathological findings associ...
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ژورنال
عنوان ژورنال: Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
سال: 1984
ISSN: 0015-6426,1882-1006
DOI: 10.3358/shokueishi.25.401